In Silico and In Vitro Studies of Mycotoxins and Their Cocktails; Their Toxicity and Its Mitigation by Silibinin Pre-Treatment

In Silico and In Vitro Studies of Mycotoxins and Their Cocktails; Their Toxicity and Its Mitigation by Silibinin Pre-Treatment

Mycotoxins found in randomly selected commercial milk thistle dietary supplement were evaluated for their toxicity in silico and in vitro. Using in silico methods, the basic physicochemical, pharmacological, and toxicological properties of the mycotoxins were predicted using ACD/Percepta. The in vit...

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Bibliographic Details
Main Authors: Van Nguyen Tran, Jitka Viktorova, Katerina Augustynkova, Nikola Jelenova, Simona Dobiasova, Katerina Rehorova, Marie Fenclova, Milena Stranska-Zachariasova, Libor Vitek, Jana Hajslova, Tomas Ruml
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Toxins
Subjects:
acute toxicity
combined toxicity
genotoxicity
cell protection
silibinin
in silico prediction
co-culture models
Online Access:https://www.mdpi.com/2072-6651/12/3/148

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https://www.mdpi.com/2072-6651/12/3/148

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