Impact of cerebral blood flow and amyloid load on SUVR bias

Impact of cerebral blood flow and amyloid load on SUVR bias

Abstract Background Despite its widespread use, the semi-quantitative standardized uptake value ratio (SUVR) may be biased compared with the distribution volume ratio (DVR). This bias may be partially explained by changes in cerebral blood flow (CBF) and is likely to be also dependent on the extent...

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Bibliographic Details
Main Authors: Fiona Heeman, Maqsood Yaqub, Janine Hendriks, Bart N. M. van Berckel, Lyduine E. Collij, Katherine R. Gray, Richard Manber, Robin Wolz, Valentina Garibotto, Catriona Wimberley, Craig Ritchie, Frederik Barkhof, Juan Domingo Gispert, David Vállez García, Isadora Lopes Alves, Adriaan A. Lammertsma, on behalf of the AMYPAD Consortium
Format: Article
Language:English
Published: SpringerOpen 2022-05-01
Series:EJNMMI Research
Subjects:
Alzheimer’s disease
Amyloid PET
Cerebral blood flow
Quantification
SUVR bias
Online Access:https://doi.org/10.1186/s13550-022-00898-8

Internet

https://doi.org/10.1186/s13550-022-00898-8

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