Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction

Background and Objectives Mesenchymal stem cells (MSC) have been proposed as a way to treat graft-versus-host disease based on their immunosuppressive effect. We analyzed whether regulatory T cells can be generated in co-cultures of peripheral blood mononuclear cells (PBMC) and MSC.Design and Method...

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Bibliographic Details
Main Authors: Claudia Prevosto, Marta Zancolli, Paolo Canevali, Maria Raffaella Zocchi, Alessandro Poggi
Format: Article
Language:English
Published: Ferrata Storti Foundation 2007-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/4502