microRNA-130b downregulation potentiates chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SOX9

microRNA-130b downregulation potentiates chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SOX9

Osteoarthritis (OA) is a chronic health condition. MicroRNAs (miRs) are critical in chondrocyte apoptosis in OA. We aimed to investigate the mechanism of miR-130b in OA progression. Bone marrow mesenchymal stem cells (BMSCs) and chondrocytes were first extracted. Chondrogenic differentiation of BMSC...

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Bibliographic Details
Main Authors: Penggui Zhang, Guangming Gao, Ziyu Zhou, Xuejun He
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2021-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Osteoarthritis
miR-130b
SOX9
Chondrogenic differentiation
Bone marrow mesenchymal stem cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021000400605&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021000400605&tlng=en

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