Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive <i>Escherichia coli</i> (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease

Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive <i>Escherichia coli</i> (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease

Hypersecretion of proinflammatory cytokines and dysregulated activation of the IL-23/Th17 axis in response to intestinal microbiota dysbiosis are key factors in the pathogenesis of inflammatory bowel diseases (IBD). In this work, we studied how <i>Lactobacillus</i> and <i>Bifidobac...

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Bibliographic Details
Main Authors: Gabriella Leccese, Alessia Bibi, Stefano Mazza, Federica Facciotti, Flavio Caprioli, Paolo Landini, Moira Paroni
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
probiotics
AIEC
intestinal inflammation
IL-23/Th17
Crohn’s disease
ulcerative colitis
Online Access:https://www.mdpi.com/2073-4409/9/8/1824

Internet

https://www.mdpi.com/2073-4409/9/8/1824

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