Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity.

The Phospholipase D (PLD) superfamily of proteins includes a group of enzymes with nuclease activity on various nucleic acid substrates. Here, with the aim of better understanding the substrate specificity determinants in this subfamily, we have characterised the enzymatic activity and the crystal s...

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Bibliographic Details
Main Authors: Louisa Celma, Christopher Corbinais, Julien Vercruyssen, Xavier Veaute, Inès Li de la Sierra-Gallay, Raphaël Guérois, Didier Busso, Aurélie Mathieu, Stéphanie Marsin, Sophie Quevillon-Cheruel, J Pablo Radicella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5714352?pdf=render