The roles of epigenetic regulation in cholangiocarcinogenesis

Cholangiocarcinoma (CCA), a heterogeneous malignancy of bile duct epithelial cells, is characterized by aggressiveness, difficult diagnosis, and poor prognosis due to limited understanding and lack of effective therapeutic strategies. Genetic and epigenetic alterations accumulated in CCA cells can c...

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Bibliographic Details
Main Authors: Baiyin Zhong, Qicheng Liao, Xin Wang, Xiaonong Wang, Jianhong Zhang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223010818