Immunogenicity and reactogenicity of a booster dose of a typhoid conjugate vaccine (TCV) in Malawian pre-school childrenResearch in context

Immunogenicity and reactogenicity of a booster dose of a typhoid conjugate vaccine (TCV) in Malawian pre-school childrenResearch in context

Summary: Background: We assessed persistence of typhoid immunity conferred by Vi polysaccharide-tetanus toxoid (Vi-TT) conjugate vaccine (TCV) four years post-vaccination and immunogenicity of a booster dose of Vi-TT given at age five. Methods: In 2018, a phase 3 trial of Vi-TT in Malawi randomised...

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Bibliographic Details
Main Authors: Nginache Nampota-Nkomba, Osward M. Nyirenda, Shrimati Datta, Victoria Mapemba, Priyanka D. Patel, Theresa Misiri, Felistas Mwakiseghile, John M. Ndaferankhande, Bright Lipenga, Jennifer Oshinsky, Marcela F. Pasetti, Leslie P. Jamka, Melita A. Gordon, Matthew B. Laurens, Kathleen M. Neuzil
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:EClinicalMedicine
Subjects:
Typhoid conjugate vaccine
Salmonella enterica
Salmonella typhi
Typhoid fever
Malawi
Africa
Online Access:http://www.sciencedirect.com/science/article/pii/S258953702500032X

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http://www.sciencedirect.com/science/article/pii/S258953702500032X

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