Changes in innate and permissive immune responses after hbv transgenic mouse vaccination and long-term-siRNA treatment [corrected].

Changes in innate and permissive immune responses after hbv transgenic mouse vaccination and long-term-siRNA treatment [corrected].

BACKGROUND: Currently, no licensed therapy can thoroughly eradicate hepatitis B virus (HBV) from the body, including interferon α and inhibitors of HBV reverse-transcription. Small interfering RNA (siRNA) seem to be a promising tool for treating HBV, but had no effect on the pre-existing HBV covalen...

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Bibliographic Details
Main Authors: Guang-Li Ren, Guang-Yu Huang, Hong Zheng, Ying Fang, Heng-Hao Ma, Man-Chun Xu, Hong-Bin Zhang, Wei-Yun Zhang, Ya-Gang Zhao, Da-Yong Sun, Wen-Kui Hu, Jian Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3589400?pdf=render

Internet

http://europepmc.org/articles/PMC3589400?pdf=render

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