BTK Inhibition Impairs the Innate Response Against Fungal Infection in Patients With Chronic Lymphocytic Leukemia

BTK Inhibition Impairs the Innate Response Against Fungal Infection in Patients With Chronic Lymphocytic Leukemia

Infections represent a cause of morbidity and mortality in patients affected by chronic lymphocytic leukemia (CLL). Introduction of new drugs in CLL clinical practice has showed impressive efficacy, in particular those targeting BTK. Among the consistent clinical data, an increasing number of report...

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Bibliographic Details
Main Authors: Stefania Fiorcari, Rossana Maffei, Daniela Vallerini, Lydia Scarfò, Patrizia Barozzi, Monica Maccaferri, Leonardo Potenza, Paolo Ghia, Mario Luppi, Roberto Marasca
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
chronic lymphocytic le
ibrutinib
macrophages
fungal infection
immunomodulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02158/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02158/full

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