SAP deficiency aggravates periodontitis possibly via C5a-C5aR signaling-mediated defective macrophage phagocytosis of Porphyromonas gingivalis

SAP deficiency aggravates periodontitis possibly via C5a-C5aR signaling-mediated defective macrophage phagocytosis of Porphyromonas gingivalis

Introduction: Serum amyloid P component (SAP) regulates the innate immune system and microbial diseases. Periodontitis is an inflammatory oral disease developed by the host immune system's interaction with the dysbiotic oral microbiome, thereby SAP could play a role in periodontitis pathogenici...

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Bibliographic Details
Main Authors: Liping Wang, Dongliang Liang, Yinyin Huang, Yunxin Chen, Xiaocong Yang, Zhijun Huang, Yiqin Jiang, Hanfu Su, Lijing Wang, Janak L. Pathak, Linhu Ge
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Advanced Research
Subjects:
Serum amyloid P component
Periodontitis
Macrophages
Porphyromonas gingivalis
C5a-C5aR signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222002181

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http://www.sciencedirect.com/science/article/pii/S2090123222002181

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