Use of a MAIT Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model of Vibrio cholerae O1 Vaccination
Background: Mucosal-associated invariant T (MAIT) cells are innate-like T cells enriched in the mucosa with capacity for B-cell help. We hypothesize that targeting MAIT cells, using a MAIT-activating ligand as an adjuvant, could improve mucosal vaccine responses to bacterial pathogens such as Vibri...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Case Western Reserve University
2022-08-01
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| Series: | Pathogens and Immunity |
| Subjects: | |
| Online Access: | https://www.paijournal.com/index.php/paijournal/article/view/525 |