Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology

Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology

Abstract Synaptic degeneration is a precursor of synaptic and neuronal loss in neurodegenerative diseases such as Alzheimer’s disease (AD) and frontotemporal dementia with tau pathology (FTD-tau), a group of primary tauopathies. A critical role in this degenerative process is assumed by enzymes such...

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Detaylı Bibliyografya
Asıl Yazarlar: Deonne Taylor, Andrew Kneynsberg, Marloes van Roijen, Jürgen Götz
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2023-01-01
Seri Bilgileri:Molecular Brain
Konular:
Alzheimer’s disease
Amyloid-β
Frontotemporal dementia
Striatal-enriched tyrosine phosphatase 61 (STEP61)
Microtubule-associated protein tau
Transgenic mice
Online Erişim:https://doi.org/10.1186/s13041-023-00994-3

Internet

https://doi.org/10.1186/s13041-023-00994-3

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