Conformational sampling and kinetics changes across a non-Arrhenius break point in the enzyme thermolysin
Numerous studies have suggested a significant role that protein dynamics play in optimizing enzyme catalysis, and changes in conformational sampling offer a window to explore this role. Thermolysin from Bacillus thermoproteolyticus rokko, which is a heat-stable zinc metalloproteinase, serves here as...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC and ACA
2020-01-01
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| Series: | Structural Dynamics |
| Online Access: | http://dx.doi.org/10.1063/1.5130582 |