Functional Analysis of Mutations in Exon 9 of NF1 Reveals the Presence of Several Elements Regulating Splicing.

Functional Analysis of Mutations in Exon 9 of NF1 Reveals the Presence of Several Elements Regulating Splicing.

Neurofibromatosis type 1 (NF1) is one of the most common human hereditary disorders, predisposing individuals to the development of benign and malignant tumors in the nervous system, as well as other clinical manifestations. NF1 is caused by heterozygous mutations in the NF1 gene and around 25% of t...

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Bibliographic Details
Main Authors: Elisabete Hernández-Imaz, Yolanda Martín, Laura de Conti, German Melean, Ana Valero, Marco Baralle, Concepción Hernández-Chico
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4624989?pdf=render

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http://europepmc.org/articles/PMC4624989?pdf=render

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