The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

Abstract Background Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, causing a major risk of liver disease and hepatocellular carcinoma (HCC). Many mouse models have been tried to establish HBV infection through injection with various HBV-containing plasmids. H...

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Bibliographic Details
Main Authors: Xian Wang, Jianmin Zhu, Yong Zhang, Yue Li, Tai Ma, Qun Li, Jiegou Xu, Long Xu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Virology Journal
Subjects:
Plasmid backbone
Hepatitis B virus
Hydrodynamic injection
HBcAg
Mouse model
Online Access:http://link.springer.com/article/10.1186/s12985-018-1002-y

Internet

http://link.springer.com/article/10.1186/s12985-018-1002-y

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