Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle

Summary: Fibro/adipogenic progenitors (FAPs) are skeletal muscle stromal cells that support regeneration of injured myofibers and their maintenance in healthy muscles. FAPs are related to mesenchymal stem cells (MSCs/MeSCs) found in other adult tissues, but there is poor understanding of the extent...

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Bibliographic Details
Main Authors: Prech Uapinyoying, Marshall Hogarth, Surajit Battacharya, Davi A.G. Mázala, Karuna Panchapakesan, Carsten G. Bönnemann, Jyoti K. Jaiswal
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223015560