Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.

Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.

<h4>Background</h4>TcTLE is a nonamer peptide from Trypanosoma cruzi KMP-11 protein that is conserved among different parasite strains and that is presented by different HLA-A molecules from the A2 supertype. Because peptides presented by several major histocompatibility complex (MHC) su...

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Bibliographic Details
Main Authors: Paola Lasso, Lina Beltrán, Fanny Guzmán, Fernando Rosas, M Carmen Thomas, Manuel Carlos López, John Mario González, Adriana Cuéllar, Concepción J Puerta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0150996&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0150996&type=printable

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