Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing

Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing

Despite prolonged and intensive application, combined antiretroviral therapy cannot eradicate human immunodeficiency virus (HIV)-1 because it is harbored as a latent infection, surviving for long periods of time. Alternative approaches are required to overcome the limitations of current therapy. We...

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Bibliographic Details
Main Authors: Kazuo Suzuki, Shinichiro Hattori, Katherine Marks, Chantelle Ahlenstiel, Yosuke Maeda, Takaomi Ishida, Michelle Millington, Maureen Boyd, Geoff Symonds, David A Cooper, Seiji Okada, Anthony D Kelleher
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116301962

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http://www.sciencedirect.com/science/article/pii/S2162253116301962

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