Categorization of Cytochrome P4502D6 Activity Score by Urinary Amphetamine/Methamphetamine Ratios

Categorization of Cytochrome P4502D6 Activity Score by Urinary Amphetamine/Methamphetamine Ratios

Methamphetamine (MA) level in urine has been used for judgment in MA consumption. Metabolism and intoxication of MA are correlated with the activity of cytochrome P450 2D6 (CYP2D6). The activity score (AS) is a potential tool for predicting exposure and personalized dose of drugs metabolized by CYP2...

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Bibliographic Details
Main Authors: Jatuporn Chaichana, Manee Khamenkhetkarn, Thanapat Sastraruji, Tawachai Monum, Timothy E. O’Brien, Yutti Amornlertwatana, Churdsak Jaikang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
CYP2D6
activity score
metabolic ratio
methamphetamine
amphetamine
Online Access:https://www.mdpi.com/2218-1989/12/12/1174

Internet

https://www.mdpi.com/2218-1989/12/12/1174

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