Novel small molecule-based acetylcholinesterase (AChE) inhibitors: From biological perspective to recent developments

Novel small molecule-based acetylcholinesterase (AChE) inhibitors: From biological perspective to recent developments

Alzheimer's disease (AD) is a chronic neurodegenerative disorder that imposes a substantial socioeconomic burden globally. The increasing prevalence of AD, coupled with an incomplete understanding of its fundamental etiology and the absence of a definitive cure, has intensified research efforts...

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Bibliographic Details
Main Authors: Anjali Sobha, Anand Ganapathy, Sangeetha Mohan, Nithya Madhusoodanan, Alansheeja D. Babysulochana, Kumaran Alaganandan, Sasidhar B. Somappa
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Alzheimer's disease
Acetylcholinesterase hypothesis
Multi-target directed ligands
Small molecule inhibitors
SAR studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417424001092

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http://www.sciencedirect.com/science/article/pii/S2772417424001092

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