Stability Enhancement and Skin Permeation Application of Nicotine by Forming Inclusion Complex with β-Cyclodextrin and Methyl-β-Cyclodextrin

Stability Enhancement and Skin Permeation Application of Nicotine by Forming Inclusion Complex with β-Cyclodextrin and Methyl-β-Cyclodextrin

Nicotine is widely used in pharmaceutical industries, especially for smoking cessation in the form of transdermal patches. Nicotine gel in the patches has limitations from nicotine instability and high volatility. Thus, a nicotine preservation technique is needed. In this study, a nicotine encapsula...

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Bibliographic Details
Main Authors: Sorrawee Chulurks, Kulpavee Jitapunkul, Sasimas Katanyutanon, Pisanu Toochinda, Luckhana Lawtrakul
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Scientia Pharmaceutica
Subjects:
cyclodextrin
encapsulation
molecular modeling
nicotine
preservation
skin permeation
Online Access:https://www.mdpi.com/2218-0532/89/4/43

Internet

https://www.mdpi.com/2218-0532/89/4/43

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