Cardiac-derived extracellular matrix: A decellularization protocol for heart regeneration.

Extracellular matrix (ECM) is a fundamental component of the heart, guiding vital cellular processes during organ homeostasis. Most cardiovascular diseases lead to a remarkable remodeling of the ECM, accompanied by the formation of a fibrotic tissue that heavily compromises the heart function. Effec...

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Bibliographic Details
Main Authors: Immacolata Belviso, Anna Maria Sacco, Domenico Cozzolino, Daria Nurzynska, Franca Di Meglio, Clotilde Castaldo, Veronica Romano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0276224