Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation

Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation

The purpose of this study was to assess the parameters of doxorubicin (DOX) loaded lipid polymer hybrid nanoparticles (LPHNs) formulation development, and then the bioavailability of DOX were determined in the rabbit model, in order to evaluate the intrinsic outcome of dosage form improvement after...

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Bibliographic Details
Main Authors: Muhammad Shafique, Maqsood Ur Rehman, Zul Kamal, Rami M. Alzhrani, Sameer Alshehri, Ali H. Alamri, Mohammed Ali Bakkari, Fahad Y. Sabei, Awaji Y. Safhi, Ahmed M. Mohammed, Mohamed A. El Hamd, Saud Almawash
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
bioavailability
doxorubicin
lipid polymer hybrid nanoparticles
in vitro
in vivo
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1025013/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1025013/full

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