Humoral and cellular immunogenicity of homologous and heterologous booster vaccination in Ad26.COV2.S-primed individuals: Comparison by breakthrough infection

Humoral and cellular immunogenicity of homologous and heterologous booster vaccination in Ad26.COV2.S-primed individuals: Comparison by breakthrough infection

BackgroundWhether or not a single-dose Ad26.COV2.S prime and boost vaccination induces sufficient immunity is unclear. Concerns about the increased risk of breakthrough infections in the Ad26.COV2.S-primed population have also been raised.MethodsA prospective cohort study was conducted. Participants...

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Bibliographic Details
Main Authors: Hakjun Hyun, A-Yeung Jang, Heedo Park, Jung Yeon Heo, Yu Bin Seo, Eliel Nham, Jin Gu Yoon, Hye Seong, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim, Soo-Young Yoon, Jong Hyeon Seok, Jineui Kim, Man-Seong Park, Joon Young Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
vaccines
humoral immunity
cellular immunity
booster
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1131229/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1131229/full

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