Development and Optimization of Hyaluronic Acid-Poloxamer In-Situ Gel Loaded with Voriconazole Cubosomes for Enhancement of Activity against Ocular Fungal Infection

Development and Optimization of Hyaluronic Acid-Poloxamer In-Situ Gel Loaded with Voriconazole Cubosomes for Enhancement of Activity against Ocular Fungal Infection

Fungal eye infections are largely disseminated, especially in developing countries where they may leave over half a million people blind per year. The current study aims to boost the voriconazole antifungal efficiency via loading it as cubosomes (VZ-Cub) into hyaluronic acid and poloxamer-based ocul...

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Bibliographic Details
Main Authors: Nabil A. Alhakamy, Khaled M. Hosny, Waleed Y. Rizg, Bayan A. Eshmawi, Moutaz Y. Badr, Awaji Y. Safhi, Samar S. A. Murshid
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Gels
Subjects:
antifungal
hyaluronic acid
Box-Behnken design
voriconazole
nanocubosomes
Online Access:https://www.mdpi.com/2310-2861/8/4/241

Internet

https://www.mdpi.com/2310-2861/8/4/241

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