Nontargeted Metabolomics Revealed Novel Association Between Serum Metabolites and Incident Acute Coronary Syndrome: A Mendelian Randomization Study

Nontargeted Metabolomics Revealed Novel Association Between Serum Metabolites and Incident Acute Coronary Syndrome: A Mendelian Randomization Study

Background This study was performed to identify metabolites associated with incident acute coronary syndrome (ACS) and explore causality of the associations. Methods and Results We performed nontargeted metabolomics in a nested case‐control study in the Dongfeng‐Tongji cohort, including 500 incident...

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Bibliographic Details
Main Authors: Gaokun Qiu, Yuhui Lin, Yang Ouyang, Mingrong You, Xinjie Zhao, Hao Wang, Rundong Niu, Wending Li, Xuedan Xu, Qi Yan, Yurong Liu, Yingmei Li, Handong Yang, Xiulou Li, Meian He, Xiaomin Zhang, Xiao‐Ou Shu, Guowang Xu, Tangchun Wu
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
acute coronary syndrome
Mendelian randomization
nested case‐control study
nontargeted metabolomics
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.028540

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.122.028540

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