Cardiac endothelial ischemia/reperfusion injury-derived protein damage-associated molecular patterns disrupt the integrity of the endothelial barrier

Cardiac endothelial ischemia/reperfusion injury-derived protein damage-associated molecular patterns disrupt the integrity of the endothelial barrier

Human cardiac microvascular endothelial cells (HCMECs) are sensitive to ischemia and vulnerable to damage during reperfusion. The release of damage-associated molecular patterns (DAMPs) during reperfusion induces additional tissue damage. The current study aimed to identify early protein DAMPs in hu...

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Bibliographic Details
Main Authors: Sarawut Kumphune, Porrnthanate Seenak, Nitchawat Paiyabhrom, Worawat Songjang, Panyupa Pankhong, Noppadon Jumroon, Siriwan Thaisakun, Narumon Phaonakrop, Sittiruk Roytrakul, Wachirawadee Malakul, Arunya Jiraviriyakul, Nitirut Nernpermpisooth
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Cardiac microvascular endothelial cells
Damage-associated molecular patterns
Ischemia reperfusion injury
Endothelial nitric oxide synthase
Vascular endothelial-cadherin
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024006315

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http://www.sciencedirect.com/science/article/pii/S2405844024006315

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