Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer

Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer

Dephosphorylation of transcription factor EB (TFEB) at Ser142 and Ser138 determines its nuclear localization and transcriptional activity. The link between TFEB-associated genes and colorectal cancer (CRC) progression and prognosis remains unclear. To systematically identify the targets of TFEB, we...

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Bibliographic Details
Main Authors: Zijia Huang, Sheng Zhu, Ziqin Han, Chen Li, Junze Liang, Yang Wang, Shuixing Zhang, Jing Zhang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
TFEB
DIA-based proteomics
vesicular endocytic trafficking
colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/15/3/744

Internet

https://www.mdpi.com/2072-6694/15/3/744

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