Maintenance over Time of the Effect Produced by Esmolol on the Structure and Function of Coronary Arteries in Hypertensive Heart Diseases

We previously observed that esmolol treatment for 48 h reduced vascular lesions in spontaneously hypertensive rats (SHRs). Therefore, we investigated whether this beneficial effect is persistent after withdrawal. Fourteen-month-old SHRs (SHR-Es) were treated with esmolol (300 μg/kg/min) or a vehicle...

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Main Authors: Raquel Martín-Oropesa, Pilar Rodríguez-Rodríguez, Laia Pazó-Sayós, Ana Arnalich-Montiel, Silvia Magdalena Arribas, Maria Carmen González, Begoña Quintana-Villamandos
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/10/2042