A Novel Approach Based on Metabolomics Coupled With Intestinal Flora Analysis and Network Pharmacology to Explain the Mechanisms of Action of Bekhogainsam Decoction in the Improvement of Symptoms of Streptozotocin-Induced Diabetic Nephropathy in Mice

A Novel Approach Based on Metabolomics Coupled With Intestinal Flora Analysis and Network Pharmacology to Explain the Mechanisms of Action of Bekhogainsam Decoction in the Improvement of Symptoms of Streptozotocin-Induced Diabetic Nephropathy in Mice

Bekhogainsam decoction (BHID), a representative prescription for the treatment of diabetes mellitus (DM) and diabetic complications in both traditional Korean and Chinese medicine, was examined for its ability to ameliorate diabetic nephropathy (DN), and its mechanism of action was evaluated by meta...

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Bibliographic Details
Main Authors: Xianglong Meng, Junnan Ma, An Na Kang, Seok Yong Kang, Hyo Won Jung, Yong-Ki Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Bekhogainsam decoction
diabetic nephropathy
metabolomics
gut microbiota
network pharmacology
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00633/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00633/full

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