A comparative study on the effect of dopamine vs phenylephrine in improving the cutaneous analgesic effect of mexiletine in rats

Abstract Background The present study aimed to compare the effects of the combined administration of two adjuvants, dopamine and phenylephrine, on the cutaneous analgesic effect and duration of mexiletine in rats. Methods Nociceptive blockage was evaluated by the inhibition of response to skin pinpr...

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Bibliographic Details
Main Authors: Kesong Zheng, Mingming Han, Fang Kang, Chengwei Yang, Juan Li
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Perioperative Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13741-023-00314-2