Comprehensive analysis of ferroptosis-related gene signatures as a potential therapeutic target for acute myeloid leukemia: A bioinformatics analysis and experimental verification

Comprehensive analysis of ferroptosis-related gene signatures as a potential therapeutic target for acute myeloid leukemia: A bioinformatics analysis and experimental verification

BackgroundFerroptosis plays an important role in the development of acute myeloid leukemia (AML); however, the exact role of ferroptosis-related genes in the prognosis of AML patients is unclear.MethodsRNA sequencing data and the clinicopathological characteristics of AML patients were obtained from...

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Bibliographic Details
Main Authors: Zhiyuan Zheng, Xiaoying Hong, Xiaoxue Huang, Xiandong Jiang, He Jiang, Yingying Huang, Wei Wu, Yan Xue, Donghong Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
ferroptosis
acute myeloid leukemia
gene signatures
prognosis
The Cancer Genome Atlas
sulfasalazine
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.930654/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.930654/full

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