Therapeutic effects of CO-releaser/Nrf2 activator hybrids (HYCOs) in the treatment of skin wound, psoriasis and multiple sclerosis

Therapeutic effects of CO-releaser/Nrf2 activator hybrids (HYCOs) in the treatment of skin wound, psoriasis and multiple sclerosis

Carbon monoxide (CO) produced by heme oxygenase-1 (HO-1) or delivered by CO-releasing molecules (CO-RMs) exerts anti-inflammatory action, a feature also exhibited by the nuclear factor erythroid 2-related factor 2 (Nrf2), a master regulator of the stress response. We have recently developed new hybr...

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Bibliographic Details
Main Authors: Zeina El Ali, Anthony Ollivier, Sylvie Manin, Michael Rivard, Roberto Motterlini, Roberta Foresti
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Heme oxygenase-1 (HO-1)
Carbon monoxide (CO)
CO-Releasing molecules (CO-RMs)
Nrf2
Inflammation
Hybrid molecules
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720304328

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http://www.sciencedirect.com/science/article/pii/S2213231720304328

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