Opposite Expression Patterns of Spry3 and p75NTR in Cerebellar Vermis Suggest a Male-Specific Mechanism of Autism Pathogenesis

Opposite Expression Patterns of Spry3 and p75NTR in Cerebellar Vermis Suggest a Male-Specific Mechanism of Autism Pathogenesis

Autism is a genetically complex neurobehavioral disorder with a population prevalence of more than 1%. Cerebellar abnormalities, including Purkinje cell deficits in the vermis, are consistently reported, and rodent models of cerebellar dysfunction exhibit features analogous to human autism. We previ...

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Bibliographic Details
Main Authors: Zhenfei Ning, John M. Williams, Romika Kumari, Pavel V. Baranov, Tom Moore
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Psychiatry
Subjects:
autism
cerebellum
SPRY3
p75NTR
pseudoautosomal region
TMLHE
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00416/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2019.00416/full

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