Effect of F-Actin Organization in Lamellipodium on Viscoelasticity and Migration of Huh-7 Cells Under pH Microenvironments Using AM-FM Atomic Force Microscopy

Effect of F-Actin Organization in Lamellipodium on Viscoelasticity and Migration of Huh-7 Cells Under pH Microenvironments Using AM-FM Atomic Force Microscopy

Cytoskeleton is responsible for fundamental cellular processes and functions. The filamentous actin (F-actin) is a key constituent of the cytoskeleton system which is intrinsically viscoelastic and greatly determines the mechanical properties of cells. The organization and polymerization of F-actin...

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Bibliographic Details
Main Authors: Miao Chen, Wenpeng Zhu, Zhihua Liang, Songyou Yao, Xiaoyue Zhang, Yue Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physics
Subjects:
amplitude modulation-frequency modulation atomic force microscopy
living cancer cells
viscoelasticity gradient
F-actin cytoskeleton
lamellipodium
pH microenvironments
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2021.674958/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2021.674958/full

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