Non-Rodent Genetic Animal Models for Studying Tauopathy: Review of <em>Drosophila</em>, Zebrafish, and <em>C. elegans</em> Models

Non-Rodent Genetic Animal Models for Studying Tauopathy: Review of <em>Drosophila</em>, Zebrafish, and <em>C. elegans</em> Models

Tauopathy refers to a group of progressive neurodegenerative diseases, including frontotemporal lobar degeneration and Alzheimer’s disease, which correlate with the malfunction of microtubule-associated protein Tau (MAPT) due to abnormal hyperphosphorylation, leading to the formation of intracellula...

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Bibliographic Details
Main Authors: Hoi-Khoanh Giong, Manivannan Subramanian, Kweon Yu, Jeong-Soo Lee
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
tauopathy
pathophysiology
<i>Drosophila</i>
zebrafish
<i>C. elegans</i>
advantages
Online Access:https://www.mdpi.com/1422-0067/22/16/8465

Internet

https://www.mdpi.com/1422-0067/22/16/8465

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