Effect of Exportin 1/XPO1 Nuclear Export Pathway Inhibition on Coronavirus Replication

Effect of Exportin 1/XPO1 Nuclear Export Pathway Inhibition on Coronavirus Replication

The nucleocytoplasmic transport of proteins using XPO1 (exportin 1) plays a vital role in cell proliferation and survival. Many viruses also exploit this pathway to promote infection and replication. Thus, inhibiting the XPO1-mediated nuclear export pathway with selective inhibitors has a diverse ef...

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Bibliographic Details
Main Authors: Masmudur M. Rahman, Bereket Estifanos, Honor L. Glenn, Ami D. Gutierrez-Jensen, Karen Kibler, Yize Li, Bertram Jacobs, Grant McFadden, Brenda G. Hogue
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Viruses
Subjects:
XPO1
exportin 1
nuclear export inhibitor
coronavirus
mouse hepatitis virus
SARS-CoV-2
Online Access:https://www.mdpi.com/1999-4915/17/2/284

Internet

https://www.mdpi.com/1999-4915/17/2/284

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