WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

Abstract Background Diabetic nephropathy (DN) is prevalent in patients with diabetes. N 6-methyladenosine (m6A) methylation has been found to cause modification of nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing (NLRP) 3, which is involved in cell pyroptos...

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Bibliographic Details
Main Authors: Jianzi Lan, Bowen Xu, Xin Shi, Qi Pan, Qing Tao
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
WTAP
NLRP3
Pyroptosis
High glucose
N 6-methyladenosine
Inflammation
Online Access:https://doi.org/10.1186/s11658-022-00350-8

Internet

https://doi.org/10.1186/s11658-022-00350-8

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