Targeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase

Formation of active HIV-1 reverse transcriptase (RT) proceeds via a structural maturation process that involves subdomain rearrangements and formation of an asymmetric p66/p66′ homodimer. These studies were undertaken to evaluate whether the information about this maturation process can be used to i...

Повний опис

Бібліографічні деталі
Автори: Thomas W. Kirby, Scott A. Gabel, Eugene F. DeRose, Lalith Perera, Juno M. Krahn, Lars C. Pedersen, Robert E. London
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2023-11-01
Серія:Biomolecules
Предмети:
Онлайн доступ:https://www.mdpi.com/2218-273X/13/11/1603