Inactivation of the Rgg2 transcriptional regulator ablates the virulence of Streptococcus pyogenes.

Inactivation of the Rgg2 transcriptional regulator ablates the virulence of Streptococcus pyogenes.

Streptococcus pyogenes adapts to different niches encountered in the human host via the activity of numerous regulatory proteins including the Rgg family of transcriptional regulators. The S. pyogenes chromosome encodes four Rgg paralogues designated Rgg1 (RopB), Rgg2 (MutR), Rgg3, and Rgg4 (ComR)....

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Bibliographic Details
Main Authors: Anastasia A Zutkis, Srivishnupriya Anbalagan, Michael S Chaussee, Alexander V Dmitriev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259489?pdf=render

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http://europepmc.org/articles/PMC4259489?pdf=render

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