Impact of Dose, Sex, and Strain on Oxaliplatin-Induced Peripheral Neuropathy in Mice

Impact of Dose, Sex, and Strain on Oxaliplatin-Induced Peripheral Neuropathy in Mice

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose limiting, and long-lasting side effect of chemotherapy treatment. Unfortunately, no treatment has proven efficacious for this side effect. Rodent models play a crucial role in the discovery of new mechanisms underlying the initiatio...

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Bibliographic Details
Main Authors: Urszula O. Warncke, Wisam Toma, Julie A. Meade, Abigail J. Park, Danielle C. Thompson, Martial Caillaud, John W. Bigbee, Camron D. Bryant, M. Imad Damaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pain Research
Subjects:
oxaliplatin
neuropathy
strain differences
pre-clinical CIPN model
behavioral assay
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2021.683168/full

Internet

https://www.frontiersin.org/articles/10.3389/fpain.2021.683168/full

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