Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis

ADAM17, a prominent member of the “Disintegrin and Metalloproteinase” (ADAM) family, controls vital cellular functions through the cleavage of transmembrane substrates, including epidermal growth factor receptor (EGFR) ligands such as transforming growth factor (TGF)-alpha and Epiregulin (EREG). Sev...

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Bibliographic Details
Main Authors: Maria Sperrhacke, Sinje Leitzke, Björn Ahrens, Karina Reiss
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/8/720