Drug-Primed Reinstatement of Cocaine Seeking in Mice: Increased Excitability of Medium-Sized Spiny Neurons in the Nucleus Accumbens

To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus accumbens) before and after acute application of coc...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Yao-Ying Ma, Sandy M. Henley, Jeff Toll, James D. Jentsch, Christopher J. Evans, Michael S. Levine, Carlos Cepeda
Format: Artikel
Sprache:English
Veröffentlicht: Taylor & Francis 2013-09-01
Schriftenreihe:ASN Neuro
Online Zugang:https://doi.org/10.1042/AN20130015