Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway

Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway

Abstract Background Sevoflurane, an inhalational general anesthetic, has become one of the most widely used inhalational anesthetics in surgery. However, previous studies have found that sevoflurane anesthesia can trigger an inflammatory response, resulting in secondary damage. Dexmedetomidine (DEX)...

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Bibliographic Details
Main Authors: Nan Wang, Mingyu Wang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Anesthesiology
Subjects:
Dexmedetomidine
Sevoflurane
Neuroinflammation
PI3K/Akt/mTOR pathway
Online Access:http://link.springer.com/article/10.1186/s12871-019-0808-5

Internet

http://link.springer.com/article/10.1186/s12871-019-0808-5

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