The role of ribosomal DNA methylation in embryonic development, aging and diseases

Abstract The ribosomal DNA (rDNA) constitutes a remarkably conserved DNA sequence within species, located in the area of the nucleolus, and responsible for coding three major types of rRNAs (18S, 5.8S and 28S). While historical investigations into rDNA focused on its structure and coding capabilitie...

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Bibliographic Details
Main Authors: Fei Yang, Xutong Guo, Yiming Bao, Rujiao Li
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-024-00548-4