Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice

Alzheimer's disease (AD) is the most common form of dementia among the elderly with women exhibiting a higher risk than men for the disease. Due to these gender differences, there is great interest in the role that estrogens play in cognitive impairment and the onset of the classic amyloid and...

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Bibliographic Details
Main Authors: Cassia R. Overk, Pei-Yi Lu, Yue-Ting Wang, Jaewoo Choi, James W. Shaw, Gregory R. Thatcher, Elliott J. Mufson
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111003056