Systematic analysis of inheritance pattern determination in genes that cause rare neurodevelopmental diseases

Systematic analysis of inheritance pattern determination in genes that cause rare neurodevelopmental diseases

Despite recent advancements in our understanding of genetic etiology and its molecular and physiological consequences, it is not yet clear what genetic features determine the inheritance pattern of a disease. To address this issue, we conducted whole exome sequencing analysis to characterize genetic...

Full description

Bibliographic Details
Main Authors: Soojin Park, Se Song Jang, Seungbok Lee, Minsoo Kim, Hyungtai Sim, Hyeongseok Jeon, Sung Eun Hong, Jean Lee, Jeongeun Lee, Eun Young Jeon, Jeongha Lee, Cho-Rong Lee, Soo Yeon Kim, Man Jin Kim, Jihoon G. Yoon, Byung Chan Lim, Woo Joong Kim, Ki Joong Kim, Jung Min Ko, Anna Cho, Jin Sook Lee, Murim Choi, Jong-Hee Chae
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
neurodevelopmental disorder
inheritance pattern
carrier prediction
whole exome sequencing
recessive disorders
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.990015/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.990015/full

Similar Items