Strategies for Glycoengineering Therapeutic Proteins

Strategies for Glycoengineering Therapeutic Proteins

Almost all therapeutic proteins are glycosylated, with the carbohydrate component playing a long-established, substantial role in the safety and pharmacokinetic properties of this dominant category of drugs. In the past few years and moving forward, glycosylation is increasingly being implicated in...

Full description

Bibliographic Details
Main Authors: Kris Dammen-Brower, Paige Epler, Stanley Zhu, Zachary J. Bernstein, Paul R. Stabach, Demetrios T. Braddock, Jamie B. Spangler, Kevin J. Yarema
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Chemistry
Subjects:
glycoengineering
pharmacodynamics
pharmacokinetics
therapeutic
glycosylation
N-glycans
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.863118/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.863118/full

Similar Items