The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

The innate immune response is the first line of defense against viral pathogens, and in turn, many viruses have evolved strategies to evade detection by the host’s innate immune surveillance machinery. Investigation of the interplay between viruses and the innate immune response provides valuable in...

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Bibliographic Details
Main Authors: Cindy Chiang, Steve Dvorkin, Jessica J. Chiang, Rachel B. Potter, Michaela U. Gack
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00620-21